Antibiotic resistance, driven by overuse and misuse, poses a global health threat, rendering standard treatments ineffective against infections like MRSA. Resistance mechanisms include efflux pumps and enzyme inactivation. Novel approaches, such as bacteriophage therapy and CRISPR-based antimicrobials, aim to combat resistant strains.
Challenges include slow drug development and economic barriers in pharmaceutical investment. Global surveillance and stewardship programs, like those from WHO, promote responsible antibiotic use. Future solutions involve AI-driven drug discovery and combination therapies.
Ashish Vishwakarma, et al. "Antibiotic Resistance: Challenges and Solutions".
OpenJournal system, VOL 1, Issue 1, Case Study.DOI: https://doi.org/5k7291879342986878